The Genetic Disorders of Mucociliary Clearance Consortium
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University of Washington

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Margaret Rosenfeld, MD, MPH
Principal Investigator
Associate Professor, Pediatrics/Pulmonary
University of Washington School of Medicine
Division of Pulmonary Medicine
Children's Hospital and Regional Medical Center
4800 Sand Point Way NE, B-3550
Seattle, Washington 98105

Ronald Gibson, MD, PhD
Co-Investigator
Professor, Pediatrics/Pulmonary

University of Washington School of Medicine
Division of Pulmonary Medicine/CF Research Center
Children's Hospital and Regional Medical Center
4800 Sand Point Way NE, B-3550
Seattle, Washington 98105

Moira Aitken, MD
Co-Investigator
Professor of Medicine
Division of Pulmonary and Critical Care Medicine
University of Washington School of Medicine
Box 356522
Seattle, Washington 98195-6522

Contact Information:

Sharon McNamara, RN, MN
Research Coordinator
Children's Hospital and Regional Medical Center
1100 Olive Way, Suite 800
Seattle, Washington 98101
206-987-1313
206-987-5104 (fax)

Current Studies:

5901: Longitudinal Study of Primary Ciliary Dyskinesia: Participants 5-18 Years of Age

5902: Rare Genetic Disorders of the Airways: Cross-sectional Comparison of Clinical Features, and Development of Novel Screening and Genetic Tests

About Us:

Children's Hospital and Regional Medical Center

Ranked as one of the best children's hospitals in the country by U.S. News & World Report and Child magazines, Children's Hospital and Regional Medical Center serves as the pediatric referral center for Washington, Alaska, Montana and Idaho. Founded in 1907, Children's provides excellent patient care with compassion and respect, and conducts cutting-edge pediatric research. It also serves as a respected educational resource for parents and healthcare professionals alike.

Children's serves the largest geographic region of any children's hospital in the country. It has developed a network of clinics and programs, many in partnership with other providers, to better meet the health care needs of its patients closer to where they live.

Children's Hospital is formally affiliated with the University of Washington and all of its hospital-based physicians hold appointments at the University of Washington School of Medicine.

The Division of Pulmonary Medicine at Children's Hospital and Regional Medical Center

The Pulmonary Division at Children's Hospital and Regional Medical Center includes the Pediatric Pulmonary Center, the Cystic Fibrosis Center and the Sleep Clinic. The division, comprised of eleven full-time academic pediatric pulmonologists, six nurses, a dietitian, and two social workers, conducts four half-day clinics per week.

The Cystic Fibrosis Center manages 220 children with cystic fibrosis and indirectly oversees the clinical care of another 240 adults and children with cystic fibrosis at its satellites sites located in Spokane, Tacoma, Anchorage and at the University of Washington Adult Center. PCD patients are seen in the CF clinic at Children's.

University of Washington School of Medicine

The University of Washington School of Medicine is recognized for advancing medical knowledge through scientific research. Research scientists at the UW medical school explore every aspect of health and disease, from the molecular mechanisms of gene action to population studies of global illnesses.  Their work has contributed to improved understanding of the cause of diseases and to better treatments and prevention of many disorders.

The UW School of Medicine is a regional resource for Washington state, Wyoming, Alaska, Montana and Idaho - the WWAMI states - and is know nationally for its commitment to community service through the volunteer activities of its students, staff, faculty and alumni.

The distinguishing characteristic of the UW medical school is interdisciplinary collaboration. Scientists, educators, and clinicians are dedicated to helping each other reach the common goals of improving peoples' health and alleviating suffering from disease.

Division of Pulmonary and Critical Care Medicine, University of Washington

The Division, founded in 1965, is deeply committed to the missions of academic medicine, including patient care, biomedical research, and education. With 42 full-time faculty members, the Division provides high quality patient care for a wide spectrum of pulmonary and critical care illnesses. Division faculty are nationally-recognized experts in asthma, emphysema, chronic bronchitis, acute lung injury (including the acute respiratory distress syndrome or ARDS), cystic fibrosis, interstitial lung diseases, neuromuscular disorders, pulmonary hypertension, and the pulmonary complications of AIDS, as well as critical care medicine - the management of patients requiring care in an intensive care unit.

The Division has a chest clinic at each of four affiliated hospitals as well as many specialty clinics providing high quality outpatient care. These include a pulmonary fibrosis clinic, cystic fibrosis clinic, pulmonary hypertension clinic, pulmonary rehabilitation program, and neuromuscular weakness clinic. PCD patients are seen in the pulmonary clinic at the University of Washington Medical Center.

The Division's research activities are diverse and yet have tremendous depth in a number of important areas. The Division's Lung Biology Center provides a nexus for performing, coordinating, enhancing and stimulating basic research directed toward understanding the fundamental mechanisms of lung development, repair, and disease. Several other prominent research laboratories focus on molecular and cell biology, concentrating on such areas as acute lung injury and defense mechanisms against pulmonary infection.

The Division also has an outstanding fellowship program that trains young physicians to be leaders in the field of Pulmonary and Critical Care Medicine. In addition to learning the clinical skills of this field from nationally renowned experts, fellows are trained in biomedical research and in educating future generations of medical professionals. Because of the broad research interests of Division faculty, fellows can choose to develop research skills in molecular or cell biology, physiology, or clinical research.

Useful Links:

Division of Pulmonary and Critical Care Medicine, University of Washington

Pediatric Pulmonary Center, University of Washington

Children's Hospital and Regional Medical Center