The Genetic Disorders of Mucociliary Clearance Consortium
What is the G D M C C?  

Mission

The mission of the Genetic Disorders Of Mucociliary Clearance Consortium is to create and maintain a clinical research network to study rare diseases of the airways, focusing on primary ciliary dyskinesia (PCD), with rigorous diagnostic evaluations and comparative clinical studies in cystic fibrosis (CF), pseudohypoaldosteronism (PHA), and other chronic airway disease.

The consortium, which is centered at the University of North Carolina at Chapel Hill (UNC), currently consists of four primary sites, UNC; Washington University in St. Louis (Missouri); University of Washington (Seattle, Washington), and University of Colorado (Denver, Colorado), all of which have expertise in studying the genetics and pathogenesis of airways disease, design of clinical trials, and development of novel therapeutics for defective lung defenses. In this proposal, we will develop collaborative, intellectual, and methodological resources for the study of rare diseases of the airways.

Finally, the consortium plans to establish training programs in rare airways diseases, and develop regional and internet-based networks to provide information about such rare diseases to the patients, medical professionals, and lay public for education, referral, and recruitment of study subjects.