Baylor College of Medicine - Houston, TX

Contact Information:

Arthur L. Beaudet, M.D.
Chair and Professor, Department of Molecular and Human Genetics
Baylor College of Medicine
Email: abeaudet@bcm.tmc.edu

Carlos A. Bacino, M.D.
Assistant Professor
Baylor College of Medicine
Email: cbacino@bcm.tmc.edu

Christine M. Eng, M.D.
Associate Professor
Baylor College of Medicine
Email: ceng@bcm.tmc.edu

Brendan Lee, M.D., Ph.D.
Associate Professor
Baylor College of Medicine
Email: blee@bcm.tmc.edu

Daniel Glaze, M.D.
Professor
Baylor College of Medicine
e-mail: dglaze@bcm.tmc.edu

Huda Y. Zoghbi, M.D.
Professor
Baylor College of Medicine
e-mail: hzoghbi@bcm.tmc.edu

V. Reid Sutton, M.D.
Assistant Professor
Baylor College of Medicine
E-mail: vsutton@bcm.tmc.edu

Links:

Medical Genetics Laboratories
Baylor College of Medicine
Department of Molecular and Human Genetics
The Blue Bird Circle Rett Center

Current Clinical Studies:

5201: Rett Syndrome Natural History Study

5203: Angelman Syndrome Natural History Study

5204: Efficacy of a Therapeutic Treatment Trial in Angelman Syndrome

List of Publications:

1. Collins AL, Levenson JM, Vilaythong AP, Richman R, Armstrong DL, Noebels JL, David Sweatt J, Zoghbi HY. Mild overexpression of MeCP2 causes a progressive neurological disorder in mice. Hum Mol Genet. 2004 Nov 1;13(21):2679-89. Epub 2004 Sep 06.

2. Shahbazian M, Young J, Yuva-Paylor L, Spencer C, Antalffy B, Noebels J, Armstrong D, Paylor R, Zoghbi H. Mice with truncated MeCP2 recapitulate many Rett syndrome features and display hyperacetylation of histone H3. Neuron. 2002 Jul 18;35(2):243-54.

3. Neul JL, Zoghbi HY. Rett syndrome: a prototypical neurodevelopmental disorder. Neuroscientist. 2004 Apr;10(2):118-28.

4. Moretti P, Bouwknecht JA, Teague R, Paylor R, Zoghbi HY. Abnormalities of social interactions and home-cage behavior in a mouse model of Rett syndrome. Hum Mol Genet. 2005 Jan 15;14(2):205-20. Epub 2004 Nov 17.

5. Peters SU, Goddard-Finegold J, Beaudet AL, Madduri N, Turcich M, Bacino CA.  Cognitive and adaptive behavior profiles of children with Angelman Syndrome.  American Journal of Medical Genetics. 2004. 9999:1-4.

6. Peters SU, Beaudet AL, Madduri N, Bacino CA. Autism in Angelman Syndrome:  Implications for Autism Research.  Clinical Genetics Journal. 2004. Jul,128(2):110-3.