Salivary Gland Carcinomas Consortium

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What is Adenoid Cystic Carcinoma (ACC)?

Adenoid Cystic Carcinoma is the second most common salivary carcinoma. It comprises 15-23% of all salivary carcinoma. These tumors are characterized by protracted and relentless clinical behavior.

Who gets ACC?

ACC occurs in young and middle age adults, with a slight trend towards females affected more often than males.

What causes ACC?

The cause of ACC is unknown.

How is ACC diagnosed?

Typically these present as a lump of the parotid gland, submandibular gland, mouth or throat and may also include facial paralysis or numbness. A diagnosis is made after a biopsy of the affected tissue(s).

What is/is there treatment for ACC?

Currently, the standard practice is complete surgical excision, and most patients may also undergo post-operative radiation therapy. However, many patients develop recurrence and/or metastasis in 5 to 10 years.